Titan Spine Announces the Release of Cellular Data on Its Surface Technology

Published: May 01, 2012

MEQUON, Wis.--(BUSINESS WIRE)--Titan Spine, a medical device surface technology company focused on the development of innovative spinal interbody fusion implants, announced today that an article published in The Spine Journal reports in-vitro data that demonstrates a superior bone-forming response to the company’s unique titanium implant surface when compared to smooth titanium and Polyetheretherketone (PEEK). In particular, the peer-reviewed data shows that Titan Spine’s surface, which features a proprietary, patent-protected combination of textures on the macro, micro, and nano levels, significantly increased osteoblast maturation and local production of bone morphogenetic proteins (BMP’s). The authors, led by Barbara Boyan, Ph.D., Professor of Biomedical Engineering at the Institute for Bioengineering and Bioscience, Georgia Institute of Technology, conclude that “modifying surface structure is sufficient to create an osteogenic environment that could enhance bone formation and implant stability, without addition of exogenous growth factors.”

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