Hansa Biopharma Completes Enrollment in Anti-GBM
The completion of enrollment in the anti-GBM study marks an important milestone for the Company's expansion outside transplantation. Anti-GBM is a rare immunological disease with a significant unmet medical need
LUND, Sweden, Jan. 27, 2020 /PRNewswire/ -- Hansa Biopharma, the leader in immunomodulatory enzyme technology for rare IgG mediated diseases, today announced that the patient enrollment in an investigator-initiated phase 2 study to evaluate safety, tolerability and efficacy of imlifidase in 15 patients with severe Anti-GBM antibody disease has now been completed. A first data read out is expected in the third quarter of 2020.
"I am very pleased that we have now completed the enrollment of patients in the Anti-GBM antibody disease study. This marks an important milestone in Hansa Biopharma's efforts to develop potentially lifesaving and lifealtering therapies for patients with rare immunological diseases within a range of therapeutic areas, where there is a significant unmet medical need," says Søren Tulstrup, President and CEO, Hansa Biopharma. "Anti-GBM is the first IgG-mediated disease outside transplantation, where imlifidase is being investigated to potentially stop an immunologic attack."
Anti-GBM antibody disease, also known as Goodpasture's disease, is a severe kidney disease where the immune system mistakenly develops IgG-antibodies, resulting in an acute immune attack on the kidneys and in some patients also on the lungs. Severe Anti-GBM antibody disease may progress to renal failure or death. Most of the patients are experiencing significant loss of kidney function requiring chronic dialysis and kidney transplantation. Anti-GBM antibody disease affects roughly one in a million annually.
Hansa Biopharma was granted orphan drug designation for imlifidase for Anti-GBM antibody disease in both the EU and the US in 2018.
For further information, please contact:
Klaus Sindahl, Head of Investor Relations
Mobile: +46-(0)-709-298 269
Rolf Gulliksen, Head of Corporate Communications
Mobile: +46-(0)-733-328 634
This information was brought to you by Cision http://news.cision.com
The following files are available for download:
Hansa Biopharma completes enrollment in anti-GBM
SOURCE Hansa Biopharma AB
Company Codes: Berlin:24H, Bloomberg:HNSA@SS, ISIN:SE0002148817, LSE:0RC7, Mexico:HNSA, OTC-PINK:HNSBF, RICS:HNSA.ST, Frankfurt:24H, Stockholm:HNSA, Stuttgart:24H