Blood-Brain Barrier Market Size to Reach Valuation of USD 7.40 Billion in 2028 Growing at a CAGR of 24.8%, according to Emergen Research

The global blood-brain barrier market size is expected to reach USD 7.40 Billion in 2028 and register a steady CAGR during the forecast period, according to latest analysis by Emergen Research. Growing awareness regarding neurological disorders, increasing healthcare expenditure, advancements in medical technology, and increasing investment in blood-brain barrier technology development are some key factors driving market revenue growth. Blood-brain barrier plays an essential role in protecting the brain from harmful compounds and blood-borne disorders. It blocks the flow of compounds from circulatory systems to the Cerebrospinal Fluid (CSF) or brain by exchanging particular components controlled by BBB or blood CSF barrier. This makes treatment for brain disorders complex due to the specialized uptake of drugs by the blood-brain barrier.

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Recent advancements in drug delivery techniques enable drugs to be transferred directly to cerebrospinal fluids. There are several approaches to create a passage for delivering drugs to the brain such as passive diffusion and bispecific antibody RMT approach, Trojan horse approach, and increasing permeability. In Trojan horse approach, the drug is merged to a molecule that is able to cross the blood-brain barrier through a transporter protein.

Some Key Findings From the Report:

  • In Feb 2021, Denali Therapeutics completed a phase 1 trial of a broad portfolio of product candidates that are engineered to cross the blood-brain barrier for neurodegenerative diseases.
  • Increasing permeability segment is expected to register a faster revenue CAGR as compared to other technology segments throughout the forecast period. This can be attributed to rising focus on research activities for treatment of many neurological and central nervous system disorders.
  • North America accounted for a 32.3% revenue share in the global market in 2020. Major prevalence of Hunter’s Syndrome and Alzheimer's Disease, and growing adoption of advanced techniques for treating acute neurological disorders are major factors driving revenue growth of the market in this region.
  • Key players operating in the market are Allon Therapeutics, Inc., Angiochem Inc., Armagen Technologies, Inc., Bristol-Myers Squibb, BiOasis Technologies, Inc., Sanofi Genzyme, CarThera, Cephalon Inc., Nanomerics, and F. Hoffman La-Roche AG.

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For the purpose of this report, Emergen Research has segmented the global blood-brain barrier (BBB) market based on application, technology, end-use, and by region:

  • Application Outlook (Revenue, USD Billion; 2018–2028)
  • Alzheimer’s Disease
  • Epilepsy
  • Parkinson’s Disease
  • Multiple Sclerosis
  • Hunter’s Syndrome
  • Brain Cancer
  • Technology Outlook (Revenue, USD Billion; 2018–2028)
    • Bispecific Antibody RMT Approach
    • Trojan Horse Approach
    • Increasing Permeability
    • Passive Diffusion
    • Others
  • End-Use Outlook (Revenue, USD Billion; 2018–2028)
    • Hospitals
    • Surgical centers
    • Research Institutes
    • Others

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  • Regional Outlook (Revenue: USD Billion; 2018–2028)
    • North America
      1. U.S.
      2. Canada
      3. Mexico
    • Europe
      1. Germany
      2. France
      3. U.K.
      4. BENELUX
      5. Italy
      6. Spain
      7. Switzerland
      8. Russia
      9. Rest of Europe
    • Asia Pacific
      1. China
      2. Japan
      3. South Korea
      4. India
      5. Rest of APAC
    • Latin America
      1. Brazil
      2. Rest of LATAM
    • Middle East & Africa
      1. Saudi Arabia
      2. UAE
      3. South Africa
      4. Turkey
      5. Rest of MEA

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About Emergen Research

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