University of Pennsylvania School of Medicine Researchers Discover a Mechanism to Explain Biological "Cross-Talk" Between 24-Hour Body Cycles and Metabolism

PHILADELPHIA – It’s well known that the body’s energy levels cycle on a 24-hour, or circadian, schedule, and that this metabolic process is fueled by oxygen. Now, researchers at the University of Pennsylvania School of Medicine have found that a protein called Rev-erb coordinates the daily cycles of oxygen-carrying heme molecules to maintain the body’s correct metabolism. The research appears online this week in Science Express in advance of print publication in Science.

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