Adamas Pharmaceuticals Issued Patent

EMERYVILLE, Calif., March 31, 2015 (GLOBE NEWSWIRE) -- Adamas Pharmaceuticals, Inc. (Nasdaq:ADMS) today announced that United States Patent and Trademark Office (USPTO) issued US Patent No. 8,987,333 entitled “Composition and Method for Treating Neurological Disease.” The claims of this patent are directed towards dosage forms that enable the osmotic delivery of amantadine for therapeutic purposes.

“We are excited with this latest addition to our patent estate,” said Gregory T. Went, Chairman and CEO of Adamas Pharmaceuticals, Inc. “It represents the ongoing protection of our pharmacokinetic-based discoveries that have enabled a variety of controlled-release amantadine formulations for the treatment of neurological disorders.”

About ADS-5102

Adamas’ most advanced wholly owned product candidate is ADS-5102 (amantadine HCl), a high dose, extended-release version of amantadine that is administered once daily at bedtime. Adamas is initially developing ADS-5102 for the treatment of levodopa-induced dyskinesia, or LID, in patients with Parkinson’s disease. LID is a complication that frequently occurs in patients after long-term treatment with levodopa, the most widely used drug for Parkinson’s disease. There are no approved drugs for the treatment of LID in the United States or Europe.

About Adamas Pharmaceuticals

Adamas Pharmaceuticals, Inc. is a specialty pharmaceutical company driven to improve the lives of those affected by chronic disorders of the central nervous system. The company achieves this by modifying the pharmacokinetic profiles of approved drugs to create novel therapeutics for use alone or in fixed-dose combination products. Adamas is currently developing its lead wholly-owned product candidate, ADS-5102, for a complication associated with the treatment of Parkinson’s disease known as levodopa-induced dyskinesia, or LID, and is evaluating other potential indications. The company’s portfolio also includes two approved products with Forest Laboratories Holdings Limited (a subsidiary of Actavis plc), Namzaric™ and Namenda XR®. Forest is responsible for marketing both products in the United States under an exclusive license from Adamas. For more information, please visit www.adamaspharma.com.

Namenda XR® is a registered trademark of Merz Pharma GmbH & Co. KGaA.

Namzaric™ is a trademark of Actavis, Inc. or its affiliates.

Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, including but not limited to, statements regarding the ongoing protection of controlled-release amantadine formulations for neurological disorders. Words such as “may,” “will,” “expect,” “anticipate,” “estimate,” “intend,” “would,” and similar expressions (as well as other words or expressions referencing future events, conditions, or circumstances) are intended to identify forward-looking statements. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in forward-looking statements, including risks relating to the competitive environment and the effectiveness of the intellectual property portfolio, as well as risks relating to Adamas’ business in general , see Adamas’ Annual Report on Form 10-K filed with the Securities and Exchange Commission on March 3, 2015.

CONTACT: For questions, please contact: Julie Wood Corporate Communications & Investor Relations Adamas Pharmaceuticals, Inc. Phone: 510-450-3528

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