LITTLETON, Colo.--(BUSINESS WIRE)--Zynex Medical Holdings, Inc. (OTCBB: ZYNX), a provider of pain management systems and electrotherapy products for medical patients with functional disability, announces an increase in its orders of 256% for March of 2007 compared to the same month last year and 304% increase in orders for the first quarter of 2007 compared to the same quarter of 2006.