XenoPort, Inc. To Release Fourth Quarter Financial Results On February 1, 2006

SANTA CLARA, Calif., Jan. 18 /PRNewswire-FirstCall/ -- XenoPort, Inc. announced today that it will release its fourth quarter and fiscal year 2005 financial results on February 1, 2006, at 4:30 p.m. Eastern Time. The Company will host a conference call at 5:00 p.m. Eastern Time that same day. A replay of the call will be available for one week following the event.

To access the conference call via the Internet, go to www.XenoPort.com. Please join the call at least 15 minutes prior to the start of the call to ensure time for any software downloads that may be required.

To access the live conference call via phone, dial 1-888-275-3514. International callers may access the live call by dialing 706-679-1417. The reference number to enter the call is 4448131.

The replay of the conference call may be accessed via the Internet, at www.XenoPort.com, or via phone at 1-800-642-1687 for domestic callers, or 706-645-9291 for international callers. The reference number to enter the replay of the call is 4448131.

About XenoPort

XenoPort, Inc. is a biopharmaceutical company focused on developing a portfolio of internally discovered product candidates that utilize the body's natural nutrient transport mechanisms to improve the therapeutic benefits of existing drugs. XenoPort's most advanced product candidate, XP13512, has successfully completed a Phase 2b clinical trial for the treatment of restless legs syndrome, or RLS, and a Phase 2a clinical trial for the management of post-herpetic neuralgia. XenoPort has also completed two Phase 1 clinical trials of XP19986, a Transported Prodrug of R-baclofen. These trials demonstrated that XP19986 was suitable for twice-a-day dosing and was well tolerated with few adverse events at the doses expected to be used in future clinical trials. XenoPort has commenced a Phase 2a clinical trial of XP19986 in gastroesophageal reflux disease, or GERD, patients.

To learn more about XenoPort, please visit the web site at www.XenoPort.com.

XenoPort is a registered U.S. trademark

Source code: XNPT2F

XenoPort, Inc.

CONTACT: Jackie Cossmon of XenoPort, Inc., +1-408-616-7295, orir@XenoPort.com

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