German researchers have used a combination of bioassay work and high-resolution mass spectrometry to pin down the source of endrocrine-disrupting behaviour in 18 bottled water products. Of 24,520 suspect chemicals, the one that showed consistent results across all tests and displayed anti-androgenic and anti-estrogenic activity is di(2-ethylhexyl) fumarate (DEHF). Endocrine-disrupting chemicals (EDCs), which interfere with an organism’s hormonal systems, have been implicated in developmental and reproductive effects seen in nature and human medicine.
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