Vasopressin should be used with great caution for the treatment of hypotension in septic shock, according to results from an international research team published today in the online open access journal Critical Care. Their experiments - conducted in pigs - show it can significantly reduce blood flow to vital organs.The peptide hormone vasopressin is being developed as a new therapy for the hemodynamic support of septic shock and vasodilatory shock due to systemic inflammatory response syndrome.