ST. LOUIS--(BUSINESS WIRE)--Nov. 23, 2005--Tripos, Inc. (Nasdaq:TRPS), a leading provider of drug discovery chemistry and informatics products and services, today announced that its file enrichment collaboration with Pfizer Inc. (NYSE:PFE) will conclude in December 2005. This will complete Tripos’ work on Pfizer’s library collection. Under the terms of the agreement, Tripos received approximately $90 million over the four-year project for the design, synthesis and purification of drug-like compounds, hit follow-up and large library production.