The xCELLigence System of Roche: A Different Way to Monitor GPCR Functions in Living Cells

PENZBERG, Germany--(BUSINESS WIRE)--A series of research studies have demonstrated the benefit of the xCELLigence System for functional screening of G-protein coupled receptors (GPCRs) activity, based on its ability to modulate the actin cytoskeleton and cell adhesion. These experiments used cell lines stably expressing human recombinant histamine 1 (H1), vasopressin 1a (V1a), recombinant dopamin 1 (D1), calcitonin, and the 5HT1A receptor (5-HT1A).
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