HEIDELBERG, September 17, 2007 – Wolf-Rüdiger Schäbitz, MD, principal investigator of the SYGNIS AXIS study, using AX200 for the treatment of acute ischemic stroke, presented an expert analysis of the Phase IIa results. AX200 was found to be safe and revealed efficacy in stroke patients. The in-depth analysis of the study data demonstrated evidence that, in particular, patients with severe strokes could benefit from AX200 treatment. Currently, more than 5 million strokes happen worldwide every year. This number increases constantly due to demographic factors. Stroke is the third leading cause of death, presenting a major socio-economic burden.