FOUNTAIN VALLEY, CALIFORNIA -- (MARKET WIRE) -- September 26, 2006 -- Sutura, Inc. (“Sutura”) (OTCBB: SUTU), a California-based medical device company, announced today that its Board of Directors had approved a reverse stock split of 1 for 300 of its common shares. The proposal will need to be approved by the stockholders, and the Board expects the reverse split to be effective on or before November 30, 2006. The reverse split is intended to stabilize the Company’s share price by decreasing the number of shares, warrants and options outstanding. Sutura, Inc. has 248,637,990 shares of common stock issued and outstanding. After the effectiveness of the reverse split, those shares will be reduced to approximately 829,395 shares of common stock issued and outstanding.