Researchers at NUI Galway have developed a super-sized model of a heart valve which may lead to a new generation of cardiovascular devices. Every year, mechanical valves are inserted into approximately 125,000 patients with heart valve disease around the world. However, the valves can lead to unnatural blood flows, which can trigger a clotting reaction. Because of this, patients with prosthetic heart valves must take medication daily, which can lead to side effects.