ST. LOUIS, April 12 /PRNewswire-FirstCall/ - Sigma-Aldrich , a leading $1.8 billion Life Science and High Technology company, announced today that more than 1,100 of its bioactive small molecules have been uploaded to the National Institutes of Health's (NIH) PubChem (http://pubchem.ncbi.nlm.nih.gov), a publicly accessible database of chemical structures and biological assay data.
"In accordance with the goals of the NIH's Molecular Libraries Roadmap Initiative, Sigma-Aldrich is committed to addressing the needs of researchers who are working to understand and chemically modulate the activities of gene products associated with disease," said Christina Shasserre, Vice President of Marketing and Business Development for Sigma-Aldrich's Research Biotechnology division. "By depositing structures into PubChem, we aim to create an important link between the cutting-edge biological data contributed by the academic screening community and the bioactive small molecules that may aid follow-up research."
Dr. Stephen Bryant, Project Director, PubChem, added: "Speaking for the PubChem team, I'm very happy to welcome Sigma-Aldrich's contribution of structures to PubChem. Users of the biological screening results in PubChem often ask how they can obtain samples of the tested compounds or reagents, and links from PubChem compounds to supplier Web sites such as Sigma-Aldrich are a great resource in this regard."
The structures represent the widely used Library of Pharmacologically Active Compounds (LOPAC1280(TM)), a collection of approved drugs and bioactive small molecules available from Sigma-Aldrich. This deposit also represents the first of several planned contributions by Sigma-Aldrich to PubChem, including several thousand additional small molecules with biological relevance.
About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Our biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. We have customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use our products. Sigma-Aldrich operates in 36 countries and has 7,500 employees providing excellent service worldwide. We are committed to Accelerating Customer Success through Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit our award-winning Web site at sigma-aldrich.com.
Cautionary Statement: This release contains forward-looking statements relating to future performance, goals, strategic actions and initiatives and similar intentions and beliefs and other statements regarding the Company's expectations, goals, beliefs, intentions and the like, which involve assumptions regarding the Company's operations and conditions in the markets the Company serves. The Company does not undertake any obligation to update these forward-looking statements.
Photo: http://www.newscom.com/cgi-bin/prnh/20050215/CGSIGMAALLOGOAP Archive: http://photoarchive.ap.orgPRN Photo Desk, photodesk@prnewswire.comSigma-AldrichCONTACT: Sean Battles of Sigma-Aldrich, +1-314-286-7616,sean.battles@sial.com
Web site: http://www.sigma-aldrich.com/
