WAYNE, Pa.--(BUSINESS WIRE)--Safeguard Scientifics, Inc. (NYSE: SFE), a holding company that builds value in growth-stage life sciences and technology companies, today announced that a previously approved 1-for-6 reverse split of its common stock will take effect on Thursday, August 27, 2009. Safeguard shares will continue to trade on the New York Stock Exchange under the symbol SFE. A new CUSIP number will be assigned to Safeguard’s common stock when the split becomes effective.