ZURICH, March 16 (Reuters) - Swiss drug maker Roche Holding AG said on Thursday it had signed up new production partners to help it increase annual production of its flu medicine Tamiflu by 100 million treatments. This would bring total production capacity to 400 million treatments a year by the end of 2006. Production partners include Albemarle Corp , Ampac Fine Chemicals LLC, API Corp, Clariant , DSM , FIS, Martek Biosciences Corp , Novasep/Dynamit Nobel, PHT International, PPG Industries , Sanofi-Aventis , Shaanxi Jiahe Phytochem Co, Siegfried Ltd . Previously announced partners: Hetero Drugs, Shanghai Pharmaceuticals.