Researchers at the University of Minnesota’s Stem Cell Institute have described how an existing genetic tool can be used to study how human embryonic stem cells differentiate. The research appears in the November 2007 issue of Experimental Biology and Medicine.Researchers know very little about how human embryonic stem cells (hESC) self-renew. To fully understand these cells’ self renewal capacity and pluripotency, and their regulation, it is necessary to efficiently generate genetically modified cells and analyze the consequences of elevated and reduced expression of genes.
