Research Provides First Whole Genome Map Of Genetic Variability In Parkinson’s Disease

Mayo Clinic researchers in collaboration with scientists at Perlegen Sciences, Inc. and funded by the Michael J. Fox Foundation for Parkinson’s Research have produced the first large-scale whole genome map of genetic variability associated with Parkinson’s disease. Their results highlight changes in 12 genes that may increase the risk for Parkinson’s disease in some people. Parkinson’s disease is a disabling and currently incurable disease that affects millions of people worldwide. Mayo Clinic and Perlegen Sciences will report their findings in The American Journal of Human Genetics. The paper was published online Friday, Sept. 9 (www.ajhg.org) and will appear in the November 2005 print issue.

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