Regeneron Pharmaceuticals, Inc. Reports Positive Phase 1 Data For The VEGF Trap In Age-Related Macular Degeneration

TARRYTOWN, N.Y.--(BUSINESS WIRE)--May 1, 2006--Regeneron Pharmaceuticals, Inc. (Nasdaq: REGN - News) announced today positive preliminary results from its phase 1 trial of the Vascular Endothelial Growth Factor (VEGF) Trap in patients with the neovascular form of age-related macular degeneration (wet AMD). In addition to meeting its primary endpoints of safety and tolerability at all dose levels, the VEGF Trap demonstrated positive preliminary efficacy results. Based on these encouraging data, the Company announced today the start of a phase 2 trial in wet AMD. The data from the phase 1 trial were presented today at the 2006 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting and are available on the Company’s web site, www.regeneron.com.

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