R-Tech Ueno: Announcement On Collaborative Development Of Therapeutic Agent For Cerebral Infarction Utilizing VAP-1 Inhibitor (RTU-009) With Autonomous University Of Barcelona And Vall d’Hebron Institute Of Research

TOKYO--(BUSINESS WIRE)--R-Tech Ueno (JASDAQ: 4573)

R-Tech Ueno, Ltd. has announced plans to conduct collaborative research with Autonomous University of Barcelona (UAB) and Vall d’Hebron Institute of Research (VHIR), in Catalonia (Spain) to develop a novel VAP-1 inhibitor (Development code: RTU-009) for treatment of cerebral infarction.

RTU-009 is a novel VAP-1 inhibitor, having an anti-inflammatory and neuroprotective effect. It is confirmed that RTU-009 has a neuroprotective effect similar to Edaravone (Radicut®), the brain protective agent, and a cerebral dysfunction improving effect when applied in combination with t-PA treatment in animal stroke models. It is currently undergoing non-clinical studies to proceed to Phase I clinical trials. Though an oral VAP-1 inhibitor named RTU-1096 is under development, RTU-009 is the novel VAP-1 inhibitor that has been developed as an injection agent targeting for treatment of acute cerebral infarction.

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