Protherics PLC Announce: Holding(s) in Company

London, UK; Brentwood, TN, US: 19 March 2007 - Protherics PLC ("Protherics" or the "Company"), the international biopharmaceutical company focused on critical care and cancer, announces that, on 16 March 2007, a notification of interest in the ordinary share capital of the Company was received from AXA Investment Managers Limited on behalf of AXA S.A. in accordance with the Transparency Obligations Directive. Details of the interest notified are as follows:
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