OXiGENE Completes Enrollment of ZYBRESTAT Phase 2 Trial in Non-Small Cell Lung Cancer

SOUTH SAN FRANCISCO, Calif., June 16, 2010 (GLOBE NEWSWIRE) -- OXiGENE, Inc. (Nasdaq:OXGN), a clinical-stage, biopharmaceutical company developing novel therapeutics to treat cancer and eye diseases, announced today that it has completed its targeted enrollment of 60 patients in the FALCON trial, a randomized, controlled Phase 2 study of ZYBRESTAT™ in patients with non-squamous non-small cell lung cancer (NSCLC). An updated safety and outcome analysis from this trial was recently presented at the 2010 Annual Meeting of the American Society of Clinical Oncology (ASCO) showing that trends towards improved outcomes were observed in response rate, progression-free survival and overall survival rates in the study arm (ZYBRESTAT combined with bevacizumab and carboplatin/paclitaxel chemotherapy) as compared with the control arm (bevacizumab and chemotherapy) of the trial. The combination regimen including ZYBRESTAT was observed to be well-tolerated with no significant cumulative toxicities when compared with the control arm of the study. OXiGENE anticipates that further data from the trial will be available later in 2010.
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