An estimated 400,000 Americans suffer from multiple sclerosis (MS), a debilitating, unpredictable disease of the central nervous system, and every week 200 more Americans are diagnosed. The inflammatory pathology of MS can be seen by counting gadolinium (Gd)-enhancing lesions on T1-weighted images or new and enlarging T2 lesions on serial MRI scans. The extent of hyperintense areas on T2-weighted images provides an indication of the overall burden of disease.