Nanoparticles of the right dimensions and shape may be the key in combating the plaque that destroys neurons and leads to symptoms associated with Alzheimer’s disease, a new report shows. University of Michigan chemical engineering professor Nicholas Kotov says the nanotechnology means can attract and capture the longer fibrils that are known to form plaque related to neurodegenerative disorders. “Both amyloid peptides and nanoparticles exhibit a strong ability to self-assemble into fibrils,” Kotov said. “We were open to any possible effect of nanoparticles on the amyloid fibrillation. We were very pleased to see amazing inhibitory effect on amyloids fibrillation which opens the door for new approaches to the development of drugs to prevent Alzheimer’s disease.”
