WASHINGTON - Gangrene was eating away Frank D. Johnson’s toes, the last stage of a little-known disease that slowly chokes off blood flow in millions of people’s legs. Dr. Richard Neville made a last-ditch attempt to avoid amputating his leg, implanting a special woven tube to replace a key clogged artery. The artificial blood vessel, coated with a blood-thinning drug to work better, is the latest treatment aimed at saving legs riddled with peripheral artery disease, or PAD. >>> Discuss This Story