A little over a year ago, the Flanders Interuniversity Institute for Biotechnology (VIB), the D. Collen Research Foundation, and the Catholic University of Leuven invested in the acquisition of a new technology provided by the zebra fish. This small aquarium fish can be used to aid the study of the function of human genes. That this investment is reaping returns is evident from the study that VIB researchers at the Catholic University of Leuven are publishing today in the renowned journal Nature. They have shown for the first time that new blood vessels do not grow in random directions, but that they are guided by specific signal molecules. This is a major step in the development of new targeted forms of therapeutic angiogenesis.