Hansen Medical Announces Closing of Public Offering of Common Stock

MOUNTAIN VIEW, CA--(Marketwire - April 21, 2010) - Hansen Medical, Inc. (NASDAQ: HNSN) today announced that it closed its previously announced underwritten public offering of 16,100,000 shares of its common stock, including 2,100,0000 shares pursuant to the full exercise of the underwriters’ over-allotment option. The net proceeds to the Company from the offering are approximately $29.8 million, after deducting the underwriting discount and commissions and estimated offering expenses.

Piper Jaffray & Co. was the sole underwriter for the offering. This press release does not constitute an offer to sell or the solicitation of an offer to buy any of the securities, nor shall there be any sale of the securities in any state in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of such state.

About Hansen Medical, Inc.

Hansen Medical, Inc., based in Mountain View, Calif., develops products and technology using robotics for the accurate positioning, manipulation and control of catheters and catheter-based technologies. Its first product, the Sensei™ Robotic Catheter system, is a robotic navigation system that enables clinicians to place mapping catheters in hard-to-reach anatomical locations within the heart easily, accurately and with stability during complex cardiac arrhythmia procedures. The Sensei system is compatible with fluoroscopy, ultrasound, 3D surface map and patient electrocardiogram data and was cleared by the U.S. Food and Drug Administration in May 2007 for manipulation and control of certain mapping catheters in electrophysiology procedures. Additional information can be found at www.hansenmedical.com.

Forward-Looking Statements

This press release contains forward-looking statements regarding, among other things, statements relating to expectations, projections, estimates, goals, plans, objectives and future events. We intend such forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in Section 21E of the Exchange Act and the Private Securities Litigation Reform Act of 1995. These statements are based on the current estimates and assumptions of our management as of the date of this press release and are subject to risks, uncertainties, changes in circumstances, assumptions and other factors that may cause actual results to differ materially from those indicated by forward-looking statements. Factors that could cause actual results to differ materially from those indicated by such forward-looking statements are described in greater detail under the heading “Risk Factors” contained in our prospectus supplement filed with the Securities and Exchange Commission on April 16, 2010 and our periodic SEC filings, including our Annual Report on Form 10-K filed with the SEC on March 16, 2010. Given these uncertainties, you should not place undue reliance on the forward-looking statements in this press release. We undertake no obligation to revise or update information herein to reflect events or circumstances in the future, even if new information becomes available.