Automated gel electrophoresis combined with liquid handling workstations vastly improves time and efficiency for sequencing and associated quality control
Reno, Nev., and Burnaby, BC. (April 23, 2018) – Hamilton Robotics is proud to integrate the LightBench® with Ranger® Technology from Coastal Genomics onto the NIMBUS® Select and all Hamilton liquid handling platforms. Together, they automate DNA protocols and enable fully automated electrophoresis for size selection or quality control. The combination brings efficiencies and savings for clinical laboratories of any size or budget.
The system is especially useful for high-throughput target enrichment of cell free DNA (cfDNA) fragments and other NGS library constructs via gel-based size selection prior to sequencing. The patent-protected Ranger Technology enables the repeatable isolation of target DNA fragments over multiple samples. By isolating and recovering specific fractions with consistently high intrinsic recovery yields exceeding 70%, researchers and clinicians can reduce or eliminate the hassle and wasted expense of sequencing off-target fragments. Walkaway automation increases confidence in consistent, accurate results and eliminates the risk of operator variability and errors that may erroneously impact results. In size selection applications, up to 12 samples may be processed simultaneously, with extracted sample recovery in about 30 minutes.
Combined LightBench and Hamilton liquid handler systems are also ideal for convenient, automated microplate-based fragment length distribution analysis and fluorescent quantitation before and after size selection. The imaging mode documents sample progression during electrophoresis for electropherogram characterization, and also enables hands-free fluorescent sample quantification in one convenient unit. Up to 384 analyses may be completed within one hour.
LightBench integrated with a Hamilton liquid handler is available from Hamilton Robotics, and the standalone version of LightBench is available through Coastal Genomics for those who do not require automation.
About Hamilton Robotics:
Hamilton Robotics, an affiliate of Hamilton Company, is a leading global manufacturer providing automated liquid handling workstations and laboratory automation technology to the scientific community. With a focus on innovative design, Hamilton products incorporate patented liquid handling technologies into a portfolio that includes liquid handling platforms, standard application-based solutions, small devices, consumables, and OEM liquid handling solutions. Known for advancing life science, clinical diagnostics, forensics and biotechnology industries, Hamilton products offer reliability, performance and flexibility. Ensuring a continuous commitment to quality, Hamilton utilizes state-of-the-art manufacturing at production facilities in Reno, Nevada and Bonaduz, Switzerland, and has earned a global ISO 9001 certification. Privately held, Hamilton maintains headquarters in Reno, Nevada; Franklin, Massachusetts; and Bonaduz, Switzerland, along with subsidiary offices throughout the world. www.hamiltoncompany.com/
About Coastal Genomics:
The “Why” behind Coastal Genomics is that good science should not hinge on the fickle nature of manual bench science. We recognize that this is a shared perspective as evidenced by the continued move to automate life science protocols. Techniques that compromise on result quality in exchange for automatability can be a viable option for some workflows. Inevitably though, the demands of new applications that are high value and high throughput in nature come to require high quality input that can only be delivered by golden standard bench techniques.
Our first commercial offering, Ranger Technology, is a proprietary hardware / software platform than enables the complete automation of gel based size selection of biomolecules, a golden standard bench technique. The system leverages real-time, full-path monitoring of the gel electrophoresis process to both inform modulation of the process and determine when to conduct a size selection operation. The result is a size selection operation that cannot be bested in terms of repeatability, discrimination, and throughput.
Coastal, Ranger and LightBench are trademarks of Coastal Genomics. All other trademarks are owned and/or registered by Hamilton Robotics in the U.S. and/or other countries. For details visit www.hamiltoncompany.com/
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For additional information, please contact:
Chere Griffin
Expression Marcom, LLC
908-818-9463
cgriffin@expressionmarcom.com
Kelli Cavallaro
Hamilton Robotics
775-858-3000 ext. 461
Kelli.Cavallaro@
Matthew Nesbitt
Coastal Genomics
604-620-1332
Matthew@coastalgenomics.com
