YOQNEAM, ISRAEL--(Marketwire - January 02, 2008) - Given Imaging Ltd. (NASDAQ: GIVN), the global leader in capsule endoscopy, today announced that it has paid its outstanding royalty obligation and accrued interest of approximately $5 million to Israel's Office of the Chief Scientist of the Ministry of Industry, Trade and Labor ("OCS"). Given Imaging was committed to pay royalties for several programs to the OCS on proceeds from sales of products that the Israeli Government participated in by way of research and development grants. This repayment will result in a one-time charge of approximately $5.7 million to the Company's income statement in the fourth quarter of 2007.