GENEART AG Release: German Patent Protects Novel Screening Method for Antiviral Therapeutics Based on Synthetic Genes

Regensburg, April 7, 2008 - GENEART AG, the global market leader in gene synthesis and specialist in the field of synthetic biology, has been awarded the patent DE 10053781 "Nucleus Export Reporter System" ("Kernexportreportersystem") by the German Patent and Trade Mark Office. In the patent, the company describes a new screening system based on in vitro synthesized virus-like reporter genes to identify a new class of antiviral drug candidates. This method allows the use of a high-throughput assay to investigate the extent to which small molecules suppress virus propagation by blocking the export of viral messenger RNA (mRNA) from the cell nucleus. Once again, this development underscores the innovative potential and the broad applicability of synthetic genes in pharmaceutical research.
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