SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Exelixis, Inc. (NASDAQ:EXEL) today announced the initiation of an investigator-sponsored trial (IST) of cabozantinib in women with hormone receptor-positive breast cancer with bone metastases. This study is currently being conducted at the Massachusetts General Hospital Cancer Center under the direction of Michaela J. Higgins, M.D., MRCPI, (Principal Investigator) and José Baselga, M.D., Ph.D. (Chief of Hematology/Oncology and Associate Director of the Massachusetts General Hospital Cancer Center). This multi-center trial will also be conducted at the Memorial Sloan-Kettering Cancer Center under the direction of Monica Fornier, M.D. (Assistant Professor), and at Dana-Farber/Brigham and Women’s Cancer Center and at Beth Israel Deaconess Medical Center under the direction of Sara M. Tolaney, M.D., M.P.H., and Steven Come M.D., respectively.