"The prevention and treatment of unsatisfactory skin scarring remains an important unmet medical need," said Lincoln Krochmal, MD, CEO & President of Excaliard Pharmaceuticals. "Unsatisfactory skin scarring can be associated with various dermatologic conditions such as hypertrophic scars and keloids, elective and reconstructive surgery, traumatic wounds, Caesarian sections and burns. We are delighted with our Phase 1 study results indicating EXC 001 delivered locally has a very impressive safety profile. We look forward to further evaluating the safety and efficacy of our novel therapeutic in Phase 2 trials for conditions in which the amelioration of scarring post-operatively would be highly desirable by the patient."
"EXC 001 is a second generation antisense medicine that inhibits fibrosis. In a variety of animal models of scar formation, EXC 001 has demonstrated significant and reproducible reductions in skin scar formation," said Nicholas Dean, PhD., Founder and Chief Scientific Officer. "EXC 001 is an exciting and novel approach to reducing skin scarring, and represents the first time an antisense medicine has been used for this significant, unmet medical need."
About Excaliard Pharmaceuticals
Excaliard Pharmaceuticals, Inc., is a venture capital-funded biotechnology company founded in 2007 focused on the development and commercialization of novel and innovative drugs for the amelioration of skin scarring and other fibrotic disorders. EXC 001 was co-discovered by Isis Pharmaceuticals, Inc. (Nasdaq: ISIS) and Excaliard, and licensed to Excaliard Pharmaceuticals.
SOURCE Excaliard Pharmaceuticals, Inc.
RELATED LINKS http://www.excaliard.com
