NEW YORK (Reuters Health) - The oral contraceptive Yasmin, plus a low-dose of the diuretic spironolactone, is a safe and effective treatment for women with severe facial acne, according to the findings of a small study. Hormones can play a role in the development of acne. “Several studies have demonstrated that combined oral contraceptives can be an effective treatment for acne in women,” Dr. Aleksandar Krunic from Northwestern University Feinberg School of Medicine, Chicago, and colleagues point out in the Journal of the American Academy of Dermatology.