ST. JOSEPH, Mich., Oct. 17 /PRNewswire/ -- GeneGo, Inc., a leading provider of software and databases for systems biology, today announced that Robert S. Dow Neurobiology Laboratories extended their MetaCore license. Scientists in RSDNL have been using MetaCore for analysis of proteomics and gene expression data for understanding ischemic brain injury and its prevention. MetaCore is an expert yet easy to use platform for functional data mining. With intuitive, one-click workflows, it provides bench biologists with a comprehensive overview of pathways, networks, functional modules and processes altered in disease and under drug treatment.
“During the past year, we have used MetaCore in analyzing our quantitative proteomic data on ischemic rodent brains,” said Dr. An Zhou, a scientist at the RSDNL. “MetaCore allows us to efficiently handle multiple sets of high throughput proteomic data with statistics and visual presentation, as well as to identify pathways and networks that are unique to different ischemic conditions of the brain.”
“Research at the Robert S. Dow Neurobiology Labs,” said Dr. Roger Simon, the director of RSDNL, “is concerned with the anatomic, physiologic and neuropathologic aspects of brain and nervous system function, with a focused emphasis on the molecular and cellular mechanisms of neuronal injury and repair that are manifest in stroke and epilepsy. The proteomic and genomic responses to ischemia and particularly the phenomenon of ischemic tolerance and its neuroprotective mechanisms in the brain, are areas of concentrated interest.” Currently there are multiple NIH-funded studies in the RSDNL that address proteomic and genomic changes in the brain after ischemia. The other areas of research interest in the RSDNL include epileptic and traumatic brain injury.”
“We are pleased to see more researchers using proteomics data as well as expression data in design of their experiments,” said Julie Bryant, Vice President of Business Development at GeneGo. “Comparing multiple data types is essential; equally important is to depict pathways and networks for biologically meaningful data integration.”
About GeneGo
GeneGo develops systems biology technology for life science research. The original computational platform allows an integration and expert analysis of different kinds of experimental data (mRNA expression, proteomics, metabolomics, microRNA assays and other phenotypic data) and relevant bioactive chemistry (metabolites, drugs, other xenobiotics) within the framework of curated biological pathways and networks. GeneGo’s flagship product, MetaCore 4.0, assists pharmaceutical scientists in the areas of target selection and validation, identification of biomarkers for disease states and toxicology. The second product, MetaDrug(TM) is designed for prediction of human metabolism, toxicity and biological effects for novel small molecules compounds. MetaBase(TM) represents the knowledge base for MetaCore. For more information, please visit the company’s web site at www.genego.com
MetaCore(TM), MetaBase(TM) and MetaDrug(TM) are trademarks of GeneGo, Inc.
GeneGo, Inc.
CONTACT: Julie Bryant, VP Business Development and Marketing of GeneGo,Inc., +1-858-756-7996, julie@genego.com
Web site: http://www.genego.com//
