Some people who take cholesterol-lowering statins may feel zapped of energy and/or experience fatigue during exercise, a new study shows. The reasons for that aren’t clear. But “if you are finding it more difficult to sustain exercise or feel more fatigued, and take statins, I think it is worthwhile to tell your doctor,” says researcher Beatrice Golomb, MD, PhD. She is an associate professor of medicine at the University of California, San Diego School of Medicine.