SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Niacin, in conjunction with statin therapy, reduces lipoprotein-associated phospholipase A2 (Lp-PLA2), an important new marker of inflammation associated with heart disease and stroke due to plaque rupture, according to a study published in the September 15, 2006, issue of The American Journal of Cardiology. The study, conducted at Tufts-New England Medical Center, evaluated 54 patients who were assigned either 1,000 mg daily extended release niacin or placebo, in addition to their existing drug regimen, primarily statins, ACE inhibitors, and aspirin.