Diabetes Drug May Hold Potential As Treatment For Epilepsy, Using Same Mechanism As Ketogenic Diet, University of Wisconsin-Madison Study

ScienceDaily (Apr. 11, 2008) — Two years ago, University of Wisconsin-Madison scientists reported they had suppressed epileptic seizures in rats by giving them a glycolytic-inhibitor, inhibiting the brain’s ability to turn sugar into excess energy and blocking the expression of seizure-related genes. The discovery was greeted with excitement and hope for a new class of drugs for epilepsy, which afflicts more than 50 million people worldwide.

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