SAN DIEGO, Oct. 12 /PRNewswire/ -- Cyntellect, Inc., a privately-held biotechnology company based in San Diego, California, announced today that the Company has been issued U.S. Patent #7,092,557. The newly issued claims further expand the use of Cyntellect's patented LEAP(TM) technology to include iterative closed-loop laser processing of cells to ensure a defined level of purity or transfection. The Company now has eight issued U.S. patents covering its core technology.
"The Company's approach to cell processing is unique, allowing various forms of processing to occur on stationary cells within well plates," explained Fred Koller, Ph.D., Cyntellect's President and Chief Technical Officer. "Because the cells are not moving, they can be re-imaged for quality control purposes between processing steps and instantaneously re-processed to meet pre-defined purity and/or transfection criteria. This automated, iterative closed-loop processing of cells is completely novel, and enables our customers to address a broad and diverse set of experimental opportunities while also ensuring they can achieve maximal cell purity, yield and molecule delivery."
LEAP is an automated instrument that combines high-speed optical imaging of cells, real-time image analysis and high-speed laser manipulation of individual live cells presented in microplate formats. Using LEAP, researchers can rapidly and selectively laser-irradiate specific cells achieving >99.9% purity. The in situ processing nature means researchers can exploit rare cell populations or cells that are typically refractory to currently available purification technologies (e.g. primary cells, patient cells or delicate cell lines) as well as more robust commonly used cell types. LEAP-based laser manipulation of cells has also been demonstrated to effectively permeabilize cells transiently without inducing cellular toxicity. This approach, called LaserFect(TM), enables introduction of a wide variety of biomolecules including ions, siRNAs, proteins and quantum dots, many of which cannot be transfected using current technologies.
About Cyntellect
Cyntellect, Inc. is a biotechnology company committed to revolutionizing the use of living cells in life science research, biopharmaceutical manufacturing and cellular therapy. Cyntellect combines expertise in high-speed cell imaging and laser-based manipulation to develop products that enable novel cell imaging, purification, and transfection capabilities to enhance the productivity of laboratory research, recombinant protein production, high-content cellular assays, functional genomics and proteomics, and cell purification, including processing of cells for therapeutic transplantation. For additional information about Cyntellect, please visit its website at www.cyntellect.com.
Cyntellect, Inc.CONTACT: Jim Linton, Chief Business Officer of Cyntellect, Inc.,+1-858-382-7678, jlinton@cyntellect.com
Web site: http://www.cyntellect.com/
