A Connecticut-based biopharmaceutical company is expanding its manufacturing plant in Rhode Island, a move expected to add jobs. Alexion Pharmaceuticals of Cheshire, Conn. will mark the start of its addition of laboratories and office space in Smithfield on Monday. Gov. Lincoln Chafee and other political leaders are expected to attend. Alexion, which now employs about 125 in Smithfield, expects to increase its work force there by about 35 percent by the end of next year.