CHARLOTTE, N.C., March 18, 2009 (GLOBE NEWSWIRE) -- Chelsea Therapeutics International, Ltd. (Nasdaq:CHTP) announced that a preliminary analysis from its recently completed 12-week Phase II clinical trial in rheumatoid arthritis (RA) demonstrated that patients treated with once daily oral doses of CH-1504 at 0.25mg, 0.50mg and 1.0mg showed comparable ACR20/50/70 response rates to patients treated with a standard 20mg oral dose of methotrexate (MTX) administered once weekly. In addition, the efficacy of CH-1504 was associated with improved tolerability and reduced hepatotoxicty compared to the MTX.
