With its LSM 5 DUO Laser Scanning Microscope, Carl Zeiss Microscopy is once again one of the winners of the much-coveted R&D 100 Award. This is the fifth time in a row that Carl Zeiss Microscopy has received this award, three for the LSM 5 family alone. The LSM 5 DUO system – a new combination of the LSM 510 META and LSM 5 LIVE confocal laser scanning microscopes which have already won several awards – enables an unparalleled variety of experiments in biomedical research. It is now possible to observe extremely demanding specimens such as living cells with fast dynamic processes in detail. Launched in November 2005, the system combines all the current high-end technologies of confocal microscopy in a single workstation.