ST. PAUL, Minn. – People with migraines have differences in an area of the brain that helps process sensory information, including pain, according to a study published in the November 20, 2007, issue of Neurology®, the medical journal of the American Academy of Neurology.The study found that part of the cortex area of the brain is thicker in people with migraine than in people who do not have the neurological disorder.