Tel-Aviv, Israel, April 27, 2007 - Neurim Pharmaceuticals Ltd today announced that the Committee for Medicinal Products in Human use (CHMP) of the European Medicines Agency (EMEA) has issued an approval recommendation for Circadin 2 mg (prolonged-release melatonin) as monotherapy for the short-term treatment of Primary Insomnia characterized by poor quality of sleep in patients who are aged 55 or over.