BEDFORD, Mass.--(BUSINESS WIRE)--N2 Biomedical LLC today announced the receipt of a Small Business Innovation Research (SBIR) Phase I grant from the National Institute of Dental & Craniofacial Research (NIDCR), to investigate a new antimicrobial biodegradable bone graft material. The project will be carried out in collaboration with Prof. Huinan Liu at the University of California at Riverside.
According to Arash Aslani, Principal Investigator, “Prevention of implant-related infections after surgical repair of traumatic craniofacial injuries is an important goal. Current materials utilized to address large bone defects, such as polymethyl methacrylate (PMMA) beads, are not ideal because they do not degrade and thus require multiple surgeries; they are also prone to infection despite the addition of antibiotics. The objective of this Phase I study is to develop a new biodegradable metallic material coupled with an innovative coating system that provides longer-term antibiotic delivery to the local environment. This technology has the potential for significantly reducing infection rates and obviating the need for a subsequent surgical procedure to remove the beads.”
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