6/23/2006 San Diego, California -- Matthew T. Witte has been promoted to the position of Senior Vice President, Marketing and Sales. In this expanded role, Matt will have overall responsibility for all sales and marketing activities for both Ligand's Pain and Oncology strategic business units. Matt joined Ligand in September 2000 as Vice President, Sales after significant senior management assignments with Roche Laboratories and Novo Nordisk. After leading the build up of professional sales forces for both the Pain Product franchise and Oncology at Ligand, he was promoted to Vice President, Marketing and Sales for our Pain Products business unit. Much of the progress of AVINZA® can be attributed to Matt's determination and leadership.