Quintessence Biosciences, Inc. Cancer Drug, QBI-139, Clears FDA Review to Start Phase I Human Trial
Published: Dec 05, 2008
Unlike conventional chemotherapies, the EVade™ Ribonuclease technology provides an opportunity to attack RNA in cancer cells, an exciting new drug target, with QBI-139, which is nearly identical to a human protein, pancreatic ribonuclease 1. In preclinical disease models, QBI-139 has shown significant tumor growth inhibition against human pancreatic, non-small cell lung, prostate, and ovarian solid tumors.
“Clearance of the IND application by the FDA represents the first major clinical development milestone for QBI-139,” said Quintessence Biosciences President Laura Strong. “We are optimistic that QBI-139 will provide a new means to help patients with cancer. There is a clear need for drugs that attack cancer in new ways and ribonuclease therapies are positioned to accomplish that goal.”
About Quintessence Biosciences, Inc.
Quintessence Biosciences, Inc. is a private biopharmaceutical company focused on development of proprietary cancer therapies based on the EVade™ Ribonuclease technology. Quintessence’s first product candidate, QBI- 139, is anticipated to enter a Phase 1 clinical trial in late 2008. The company also has a pipeline of other EVade™ Ribonuclease products in preclinical research. For more information, visit www.quintbio.com.