Nucleix Researchers Discover DNA Evidence May Easily Be Falsified Company Develops New Detection Technology for Preventing Biological Identity Theft

TEL AVIV, Israel, Aug. 17 /PRNewswire/ -- Nucleix, Ltd., an emerging life science company specializing in forensic DNA analysis, announced that company researchers have proven DNA evidence found at crime scenes can easily be falsified using basic equipment, know-how and access to DNA or a DNA database. Recognizing the need to safeguard the accuracy and credibility of DNA samples in the field of forensics, Nucleix scientists have developed a novel assay termed "DNA authentication" for combating this form of "biological identity theft" by distinguishing between in-vivo (real) and in-vitro (fake) DNA. These findings and new technology have also been published online in the forensic industry's leading peer-reviewed scientific journal, Forensic Science International: Genetics. In a paper entitled, "Authentication of Forensic DNA Samples" (1) (http://www.fsigenetics.com/article/S1872-4973(09)00099-4/abstract), Nucleix scientists demonstrate that while DNA fingerprinting is considered one of the leading forensic tools in many criminal investigations, DNA evidence can easily be falsified and planted at crime scenes prior to collection by law enforcement officers. The company has developed a state-of-the-art and scientifically-validated technology that can integrate DNA authentication into standard forensic procedure.

According to Nucleix, in vivo-generated DNA contains loci that are completely and consistently methylated and other loci that are unmethylated, differing from in vitro-synthesized DNA, which is completely unmethylated. Nucleix's novel proprietary assay can identify and differentiate between real and all potential types of fake DNA through methylation analysis of a set of genomic loci. Results of the company's research demonstrated both the current risk in sample integrity and the success of Nucleix's new approach to DNA source verification.

"We believe that DNA authentication should become an integral part of the standard forensic procedure in order to assure genuine biological material has been evaluated," said Elon Ganor, MD, Nucleix Chairman, Chief Executive Officer and co-founder. "The state-of-the-art DNA authentication technology that we developed can easily be integrated into the standard protocols currently performed in forensic laboratories to assure the authenticity of the DNA sample being genuine and not fabricated. From our research in the forensic sciences community, we believe that this application of our technology to prevent 'biological identity theft' may be just the tip of the iceberg when it comes to the potential for falsification of individual DNA."

(1) D. Frumkin, et al., Authentication of forensic DNA samples, Forensic Sci. Int. Genet. (2009), doi:10.1016/j.fsigen.2009.06.009

Nucleix, Ltd.