CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, today announced that it presented new pre-clinical data from its hypercholesterolemia program at the XVI International Symposium on Drugs Affecting Lipid Metabolism held in New York City, October 4 - 7, 2007. This program is in collaboration with UT Southwestern Medical Center at Dallas and is focused on evaluating new approaches for reducing LDL cholesterol levels using RNAi therapeutics directed to the disease target proprotein convertase subtilisn/kexin type 9, or PCSK9, a target believed to be undruggable with conventional therapeutic strategies.