CAMBRIDGE, Mass.--(BUSINESS WIRE)--Acceleron Pharma, Inc., a biopharmaceutical company developing novel therapeutics that modulate the growth of cells and tissues including red blood cells, bone, muscle, fat, and the vasculature, today announced the initiation of a Phase 1 clinical study of ACE-041, a novel angiogenesis inhibitor that binds to and prevents members of the TGF-ß superfamily from signaling through the activin receptor-like kinase 1 (ALK1) receptor. The Phase 1 trial is a multiple-dose, dose-escalating study designed to assess the safety, tolerability, pharmacokinetics, and preliminary anti-tumor activity of ACE-041 in patients with advanced cancer.
